Mewgenics was never on my radar. I didn’t follow Edmund McMillen’s past work, and I haven’t gotten into The Binding of Isaac. But, if you show me something that:
- Has tiles
- Is a roguelike
I’m probably going to like it! So, after hearing it was a “tactical RPG roguelike,” I was paying attention.
After playing it for 58 hours, Mewgenics frustrated me a ton. Mistakes are heavily punished, and carry heavy consequences. And with over 200 hours of main campaign content, it will be a while before I see the end. Yet, it’s a wholly unique experience, and as I write I want nothing more than to jump back in and play it right now.
Tactical Tiles

The moment-to-moment gameplay of Mewgenics is a tactical RPG. The battlefields themselves are quite small-scale, but the damage numbers and scaling feel at home with a proper tactics RPG. Think the arena of Into the Breach with the damage numbers and class system of Fire Emblem.
Speaking of which, the mixing and matching of classes is one of the most fun parts of the gameplay. Every class has a different style of basic attack, and a different pool of abilities to pull from. You start with the basic attack, one active ability, and one passive ability, and draft the rest of the abilities as your cats level up.
The name of the game here is combos. There are no end-all be-all abilities that will make everything easy, or that you’ll want to take 100% of the time. In every great roguelike, the answer to every question is “it depends.” I’m happy to report Mewgenics follows in the footsteps of those greats.
As you navigate a run, you’ll go to different combat arenas, shops, and events. These events often come with choices: do you sacrifice half your HP for an unknown benefit? Do you try to pass this skill check, despite there being literal stink lines coming off your cat’s stats? It’s tough to know, and the wrong choice can doom your whole run, or worse.
Roguelike… Roguelite… Rogue-ish?

The progression of Mewgenics is hard to describe. Send cats on tactical adventures that almost always yield some forward momentum. Unlock new locations, classes, and items. This is happening constantly. But, you will undoubtedly return to the same locations across multiple runs, using those new classes and items to complete quests and learn new things.
After those runs, though, Mewgenics’s hook really begins. Not only can you keep items in storage, but your cats will breed to help create your next run’s chosen ones. You’ll also need to find food and money along the way to help keep the next generation full and focused.
I was never much of a Chao Garden guy, so it surprised me how invested I was in the breeding aspects. It was fun to see what little monsters my kitty crew would create — and what random names they would get.1 It was a little awkward playing on the Steam Deck and knowing the guy next to me on the plane was watching these cats get it on, but I’m sure he would’ve understood if I told him “it was for stats.”2
Something that struck me most about this strange hybrid structure was the way it makes each run feel so consequential. When I’m playing Slay the Spire, for instance, I live my life a quarter mile at a time, almost always choosing the riskier, higher-payoff option. I either win this run or I start over, so who cares?
In Mewgenics, I was a lot more calculated. I need to get these guys home safe, because I need them to defend the house. I want them to pass on a strong ability, stat, or mutation. This cat is named “Little Man,” and that’s fucking awesome. If something were to happen to him, I’d end it all. Whatever the reason, I almost always felt a strong attachment to my cat squadron, and felt like I was calculating risk in a much different way than other roguelites.
Eternal Life

Above, you’ll see my save file. You’ll notice that aforementioned 58 hours, along with a number that may terrify you: 38% complete. I cannot believe those numbers are staring at me right now. If you are like me3, that combination of numbers might terrify you, too. But Mewgenics makes the most of every hour.
Sure, there’s a ton to see. But even without unlocking everything, there’s plenty of times you could call it quits. There’s no rush to get to the end. There’s no cutscenes with key exposition you forget if you set it down for a few months. Take your time! Hop in for a run or two every week! Maybe spend a couple hours at a time managing your cats in the house to breed your perfect soldiers with dragon wings and ADHD!
As with any roguelike, there’s bound to be plenty of repetition during this long runtime. Luckily, it’s got an incredible soundtrack to keep you humming along to. Seriously, these songs are catchy. In a genre where I usually put in earbuds with a podcast, I was turning up the volume on the Steam Deck and humming along.
Mewgenics is abrasive. There’s a ton of mechanics and combinations for both the players and enemies, losing always has permanent consequences, and it feels like the mountaintop is still so far, despite the time I’ve put in. There will be some people who just don’t click with this game.
Luckily, I’m not “some people,” and I think it’s fantastic. Let’s go 150 more hours till that file says 100%, baby.
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